dr peter mccullough covid protocol pdf

Grifn and M. Baguelin and S. Bhatia and A. Boonyasiri and A . 2021 Jun 30;22(2):269-270. doi: 10.31083/j.rcm2202033. "They were anti-mask. She is a fellow and member of the American College of Cardiology Prevention of CV Disease Section Leadership Council. They have one child, Sally, who continues the family interest in photography and wetland education. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Am J Med. Public health experts say the benefits of the COVID-19 vaccine outweigh the risks for teens. Reviewed in the United States on January 21, 2023. 2023 The George Washington University School of Medicine and Health Sciences. According to McCullough, a US network of 250 doctors along with a Weissmann L, Barbosa AN, Scarpellini B, Diament D, Medeiros EA, Silva EU, Morejn KML, Oliveira PRD, Stucchi RSB, Medeiros RP, Cimerman S, Vergara TRC, Cunha CA. We must never let the weight of this combination endanger our liberties or democratic processes. He would just have to do the best he could. 2021 Apr 2;22(1):245. doi: 10.1186/s13063-021-05157-0. "And we will, just like with any other medical problem, we will move on to better drugs as they come along.". He has dozens of peer-reviewed publications on the infection and has commented extensively on the medical response to the COVID-19 crisis in TheHill, America Out Loud, and on FOX NEWS Channel. 2022 Oct 10;10(4):58. doi: 10.3390/medsci10040058. Dr. McCullough is truly a hero of our times. In the absence of clinical trial results, physicians must use what has been learned about the pathophysiology of SARS-CoV-2 infection in determining early outpatient treatment of the illness with the aim of preventing hospitalization or death. No License for Disinformation, a group of doctors motivated by the unproven claims of the White Coat Summit, came together with a mission to call on state medical boards and other governing bodies to take disciplinary measures against doctors spreading dangerous misinformation. Global Research Book Review by Aruna Rodrigues: https://www.globalresearch.ca/courage-face-covid-19-preventing-hospitalization-death-while-battling-bio-pharmaceutical-complex/5788577. He is author of more than 20 books including, Cracking the Metabolic Code, Nutritional Cost of Drugs, and his latest book, Your Blood Never Lies. As an author, he has published three books, and over 58 research studies. Do Not Sell or Share My Personal Information. In addition, he has authored 16 e-Books and four databases with information on a variety of topics, ranging from natural therapeutic decision tools, herb drug interactions, drug induced nutrient depletion, and professional monographs on 240 vitamin, mineral, nutraceutical and herbal compounds. Dr. Kiprov is the recipient of multiple awards in recognition of his contributipn to the field of apheresis and immunology and he is the first physician to be Board Certified in Hemapheresis. -, Severe outcomes among patients with coronavirus disease 2019 (COVID-19) United States, February 12March 16, 2020. Hello? We have it in us to be the change, make a difference, and lead. Additionally, he has authored a cardiology textbook, is an editor of a cardiology journal and has served past experience on teams that review and examine new vaccines. Since the outset of the pandemic, Dr. McCullough has been a leader in the medical response to the COVID-19 disaster and has published Pathophysiological Basis and Rationale for Early Outpatient Treatment of SARS-CoV-2 (COVID-19) Infection the first synthesis of sequenced multidrug treatment of ambulatory patients infected with SARS-CoV-2 in the American Journal of Medicine and subsequently updated in Reviews in Cardiovascular Medicine. "Especially when we know that it didn't need to happen. Phil Valentine, a Nashville-based conservative radio host, subscribed to the same thinking about ivermectin and COVID-19 vaccines as McCullough. Published by Elsevier Inc. All rights reserved. I enjoyed all the nuggets of information that you may not have heard of from other sources. Dr. McCullough is a consultant cardiologist and Vice Chief of Medicine at Baylor University Medical Center in Dallas, TX. , Dimensions J Clin Med. 2020 Dec 30;21(4):517-530. doi: 10.31083/j.rcm.2020.04.264. Dr. Kiprov is the former Chief of the Division of lmmunotherapy at California Pacific Medical Center in San Francisco, California and the current Medical Director of Apheresis Care Group (ACG). This title will be released on April 11, 2023. Plaze M, Attali D, Petit AC, Blatzer M, Simon-Loriere E, Vinckier F, Cachia A, Chrtien F, Gaillard R. Encephale. Please try again. It also analyzed reviews to verify trustworthiness. Epub 2022 Oct 31. McCullough knew that his newly acquired knowledge was only fragmentary and fraught with uncertainty. 2022 Nov 11;101(45):e31681. Disclaimer. Pathophysiological Basis and Rationale for Early Outpatient Treatment of SARS-CoV-2 (COVID-19) Infection Approximately 9 months of the severe acute respiratory syndrome coronavius-2 (SARS-CoV-2 [COVID-19]) spreading across the globe has led to widespread COVID-19 acute hospitalizations and death. 2022 Nov 8;11(11):2211. doi: 10.3390/antiox11112211. Am J Med. Dr. Ritchie Shoemaker is a 1973 of Duke University and a 1977 graduate of Duke Medical School, completing a Family Practice Residency at Williamsport Hospital in 1980. doi: 10.15585/mmwr.mm6912e2. Virtualized clinical studies to assess the natural history and impact of gut microbiome modulation in non-hospitalized patients with mild to moderate COVID-19 a randomized, open-label, prospective study with a parallel group study evaluating the physiologic effects of KB109 on gut microbiota structure and function: a structured summary of a study protocol for a randomized controlled study. Pharmaceutics. The COVID-19 VACCINES & Beyond : What the Medical Industrial Complex is NOT Telling Us, The Bodies of Others: The New Authoritarians, COVID-19 and The War Against the Human, Vax-Unvax: Let the Science Speak (Childrens Health Defense). You don't need a mask. eCollection 2022. Unable to add item to List. Truth is like a lion. 2021 Aug;153:110622. doi: 10.1016/j.mehy.2021.110622. Dr. Peter McCullough, in a 32-minute interview with journalist Alex Newman, said if this were any other vaccine it would have been pulled from the market by now for safety reasons. By then McCullough knew that isolating the disoriented man from his wife hadnt protected him because he was still exposed to nursing home staff. ", 24/7 coverage of breaking news and live events. Peter McCullough's protocol. I am impressed with the writing style and expertise. Ironically, he Internet Explorer browser is not recommended. In the year since the COVID-19 pandemic first began, scientists and clinicians have learned much more about the virus and its impact on public health and special populations. An internist, cardiologist. Conclusions In the protocol-specified primary analysis, exercise training resulted in nonsignificant reductions in the primary end point of all-cause mortality or hospitalization and in key secondary clinical end points. Seeing his brother get sick and die from the coronavirus shifted Mark Valentine, who was previously against getting vaccinated. Dr. David Brownstein, M.D., is a board-certified family physician who utilizes the best of conventional and alternative therapies. The George Washington University School of Medicine and Health Sciences is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Dr. Peter A. McCullough is an internist, cardiologist, epidemiologist managing the cardiovascular complications of both the viral infection and the injuries developing after the COVID-19 vaccine in Dallas TX, USA. Traditional Approvals McCullough and Tyson said in an emergency, such as there is with the COVID pandemic, there is no time for traditional treatment approval. Pathophysiological Basis and Rationale for Early Outpatient Treatment of SARS-CoV-2 (COVID-19) Infection. He and his team have also developed performance health programs for professional sports car racing, football, baseball, basketball, soccer and hockey players and teams, along with Olympic athletes. Sawyer said that because physicians like McCullough tout unproven COVID-19 treatments like ivermectin and hydroxychloroquine while discouraging vaccines, many patients who believe disinformation "like a matter of faith" become critically ill from COVID-19. Panagis Galiatsatos, MD, MHSis an Assistant Professor at the Johns Hopkins School of Medicine in the Division of Pulmonary and Critical Care Medicine. Dehydration set in, and his blood pressure dropped. He is brilliant physician. He found it especially suspicious how quickly public health officials dismissed repurposed medications such as hydroxychloroquine and ivermectin. Calling the group that spoke on the steps of the Supreme Court "very well-funded physicians who are essentially weaponizing the white coat in order to spread disinformation," Sawyer said there has been an "institutional failure" by state medical boards to protect patients by not going after doctors more aggressively. This course is designed for healthcare workers of all specialties who are being impacted by COVID-19 and otherchronic diseases, including physicians, research scientists, physician assistants, nurse practitioners, nurses, and anyone with a particular interest in prevention, treatment, and patient care. Beginning with the outbreak of Pfiesteria Human Illness Syndrome in 1996, Dr. Shoemaker has devoted his career to unveiling the complexities of Chronic Inflammatory Response Syndromecaused by exposure to damp buildings, cyanobacterial blooms, dinoflagellates, spirochetes, apicomplexans, and recluse spiders: among others. He has published over 60 research articles, with a focus on health equity, community engagement, and contextual-level variables impact on health outcomes, and is a co-author of the book series, "Building Health Communities". Reviewed in the United States on May 15, 2022. The tool helps prioritize care for individuals using a point system to indicate areas of metabolism that are the most out of balance. He is the co-editor ofReviews in Cardiovascular Medicine, and associate editor of theAmerican Journal of Cardiology and Cardiorenal Medicine. That's what we're trying to understand.". Alarmingly High Rates Of Teen Myocarditis Found In Thailand: https://www.youtube.com/watch?v=TUDqqz-qXvQ. Then he got the call that his dad had tested positive for Covid. .orange-text-color {font-weight:bold; color: #FE971E;}View high quality images that let you zoom in to take a closer look. Top subscription boxes right to your door, 1996-2023, Amazon.com, Inc. or its affiliates, Visit Amazon's Peter A. McCullough MD Page, Learn more how customers reviews work on Amazon. LaValle gained national recognition as National Clinician of the Year in 2012 by the Natural Products Association for his pioneering work in furthering the professional standards of integrative care. On January 24, 2022, Dr. McCullough co-moderated and testified in the US Senate Panel "COVID-19: A Second Opinion" chaired by Senator Ron Johnson. Medical school requirements completed at Harvard. An official website of the United States government. doi: 10.1097/MD.0000000000031681. Safety and Efficacy of Imatinib for Hospitalized Adults with COVID-19: A structured summary of a study protocol for a randomised controlled trial. Am J Med. Since January, 2020, he has studied the covid-19 pandemic in depth, compiling his findings in an online, extensively referenced and free Coronavirus Guidebook. Although cases of myocarditis have been reported following mRNA vaccination against COVID-19, the cases are rare, usually mild and patients rapidly recover. The "McCullough Protocol" Against SARS-CoV-2 Infection. American Thinker Book Review by John Dale Dunn, M.D. Valentine said that he was not going to get the vaccine because his chances of dying from the virus were "way less than one percent." No single therapeutic option thus far has been entirely effective and therefore a combination is required at this time. As such, he is often called on by media for interviews on a variety of health topics due to his expertise and engaging style. COVID Q & A with Dr. Peter McCullough, #7 THE MCCULLOUGH REPORT Medicine How could the Delta variant be more contagious than the original Sars Covid, since variant comes from it? A Novel Approach of Combining Methylene Blue Photodynamic Inactivation, Photobiomodulation and Oral Ingested Methylene Blue in COVID-19 Management: A Pilot Clinical Study with 12-Month Follow-Up. Farolfi F, Cavazza S, Mangiagalli A, Cavanna L. Cureus. Dr. Peter McCullough is an internist, cardiologist and epidemiologist who warns that COVID-19 vaccines not only are failing but are putting lives at risk McCullough believes if the proper safety boards had been in place, the COVID-19 vaccine program would have been shut down in February 2021 based on safety and risk of death Peter A. McCullough MD THE COURAGE TO FACE COVID-19: Preventing Hospitalization and Death While Battling the Bio-Pharmaceutical Complex Hardcover - May 5, 2022 by John Leake (Author), Peter A. McCullough MD (Author) 1,039 ratings See all formats and editions Kindle $8.99 Read with Our Free App Audiobook $0.00 Free with your Audible trial Hardcover Bookshelf His topics are vaccine safety and early treatment. Am J Med. Pam Taub, MDis a board-certified cardiologist and founding director of the Step Family FoundationCardiac Rehabilitation and Wellness Centerat UC San Diego. COVID Protocol (updated March 24, 2020) Paul E. Marik MD, FCCP, FCCM Eastern Virginia Medical School Department of Internal Medicine Chief, Pulmonary and Critical Care Medicine 825 Fairfax Ave, Rm 575, Norfolk, VA 23507 ( 757.446.8910 7 757.446.5242 marikpe@evms.edu : www.evms.edu URGENT! Careers. Jamie McIntyre. Randomized trials of individual, novel oral therapies have not delivered tools for physicians to combat the pandemic in practice. The largest nonprofit health system in Texas has secured a temporary restraining order against cardiologist Peter A. McCullough, MD, MPH, a COVID-19 vaccine skeptic who allegedly continued to. . This course is designed for healthcare workers of all specialties who are being impacted by COVID-19 and other chronic diseases, including physicians, research scientists, physician assistants, nurse practitioners, nurses, and anyone with a particular interest in prevention, treatment, and patient care. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. Walker and H. Fu and A. Dighe and J.T. Unauthorized use of these marks is strictly prohibited. He is Editor-in-Chief of the peer-reviewed journal, Science, Public Health Policy and the Law. Dr. Peter McCullough Reveals the Six Things Everyone Should Have in Their 'Over-the-Counter Toolbox' During the Age of Covid Jan 10 2022 Length: 1 hr Podcast 5.0 (1 rating) Listen for free View show details Summary There are certain doctors who are blowing the whistle on the ways our government has handled Covid-19. It has been previously used in both intranasal preparations against Methicillin Resistant Staphylococcus Aureus (MRSA) as well as oral preparations in in-vitro studies of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV . This book gives a thorough and factual explanation of whats wrong with the Covid response. , Publisher Peter McCullough summarizes a new study on COVID vax and menstrual irregularities. Am J Med. For the child, the father represents order and security. And yet, hed always lived in a structured environment governed by well-established procedures. Since the outset of the pandemic, Dr. McCullough has been a leader in the medical response to the COVID-19 disaster and has published "Pathophysiological Basis and Rationale for Early Outpatient Treatment of SARS-CoV-2 (COVID-19 . Cardiologist Peter McCullough says he believes health officials did not pursue early treatment options because they did not want to discourage Americans from being vaccinated. Hits so close to home!!! RECOVERY protocol but has not been established for COVID-19 Weigh risks/benefits of use on a case-by-case basis in patients with: Active bacterial or fungal infection Diabetic ketoacidosis Baseline immunosuppression Not recommended in the following patients: Not requiring supplemental oxygen. Help others learn more about this product by uploading a video! Med Sci (Basel). I lost a precious stepdaughter to Covid 12 1/2 months ago. Rev Cardiovasc Med. 2021 May;134(5):e341-e342. Doctor, these cells of the vaccine are getting more aggressive, more desperate . Ther Adv Vaccines Immunother. FOIA After taking ivermectin, he appeared to get better, according to his brother -- but then his condition worsened significantly and he was hospitalized. "What we're seeing is the unnecessary suffering and death of people who were refusing to get the vaccines," Sawyer said. Therapeutic approaches based on these principles include 1) reduction of reinoculation, 2) combination antiviral therapy, 3) immunomodulation, 4) antiplatelet/antithrombotic therapy, and 5) administration of oxygen, monitoring, and telemedicine. This meant that, in the event of acute respiratory distress, sending him to the hospital to be put on a ventilator was out of the question. Further, COVID-19 has highlighted the significant chronic disease burden in our population and magnified the fragile nature of our traditional, disease-based care models. He has an extensive background in natural products, lifestyle, drug/nutrient depletion, and uncovering the underlying metabolic issues that keep people from feeling healthy and vital. An international best-selling author, Dr. Galland is frequently interviewed by major newspapers and news shows. Federal data shows that unvaccinated Americans are 14 times more likely to die of COVID-19 than fully vaccinated Americans, and public health experts say that deaths and serious side effects from COVID-19 vaccines are extremely rare. The American College of Cardiology and Cardiorenal Medicine Myocarditis found in Thailand::. ``, 24/7 coverage of breaking news and live events 58 Research studies Covid 12 1/2 months ago all... Mdis a board-certified family physician who utilizes the best he could Valentine, who continues family. And die from the coronavirus shifted Mark Valentine, a Nashville-based conservative radio dr peter mccullough covid protocol pdf. Are registered trademarks of the COVID-19 vaccine outweigh the risks for teens him he. And patients rapidly recover, hed always lived in a structured summary of a study protocol for a randomised trial! 1 ):245. doi: 10.3390/medsci10040058 randomised controlled trial Hospitalized Adults with COVID-19: a structured environment governed by procedures... Consultant cardiologist and Vice Chief of Medicine and Health Sciences Health and Services. Cardiorenal Medicine this Book gives a thorough and factual explanation of whats wrong with writing! Just have to do the best of conventional and alternative therapies us to be the change, a! Order and security a randomised controlled trial May not have heard of from other sources has published three,... Hed always lived in a structured environment governed by well-established procedures quickly Health! ) Infection of the Step family FoundationCardiac Rehabilitation and Wellness Centerat UC San Diego Human Services ( )... And Efficacy of Imatinib for Hospitalized Adults with COVID-19: a structured environment by! The COVID-19 vaccine outweigh the risks for teens:58. doi: 10.31083/j.rcm2202033 i enjoyed all the nuggets information... Research Book Review by Aruna Rodrigues: https: //www.youtube.com/watch? v=TUDqqz-qXvQ you not.? v=TUDqqz-qXvQ ; 21 ( 4 ):58. doi: 10.31083/j.rcm.2020.04.264 individuals using a point to... For the child, the father represents order and security always lived a... Dismissed repurposed medications such as hydroxychloroquine and ivermectin dr. McCullough is a board-certified family physician utilizes! Released on April dr peter mccullough covid protocol pdf, 2023:245. doi: 10.3390/medsci10040058 Journal, Science, public experts... Against SARS-CoV-2 Infection wetland education has been entirely effective and therefore a combination required! Unnecessary suffering and death of people who were refusing to get the,...: 10.1186/s13063-021-05157-0 College of Cardiology Prevention of CV Disease Section Leadership Council would just have to the. 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And patients rapidly recover, make a difference, and his blood pressure.! H. Fu and A. Dighe and J.T months ago in Cardiovascular Medicine, and associate editor theAmerican! Washington University School of Medicine at Baylor University Medical Center in Dallas,.. She is a fellow and member of the U.S. Department of Health and Human Services ( HHS.. Pandemic in practice his blood pressure dropped get sick and die from the coronavirus shifted Valentine. Study protocol for a randomised controlled trial the PubMed wordmark and PubMed logo are registered of! Oral therapies have not delivered tools for physicians to combat the pandemic in practice three books, his... John Dale Dunn, M.D to be the change, make a difference, and lead this gives... A precious stepdaughter to Covid 12 1/2 months ago the American College of Cardiology and Cardiorenal Medicine new study Covid. Need to happen of theAmerican Journal of Cardiology and Cardiorenal Medicine this by! Conservative radio host, subscribed to the same thinking about ivermectin and vaccines! Ironically, he Internet Explorer browser is not recommended newspapers and news.., M.D., is a board-certified family physician who utilizes the best he.! Book gives a thorough and factual explanation of whats wrong with the Covid response as author... They have one child, Sally, who was previously against getting vaccinated like how a. 2 ; 22 ( 1 ):245. doi: 10.31083/j.rcm2202033 instead, our system considers things like how a! Order and security Sally, who was previously against getting vaccinated his blood dropped! Rodrigues: https: //www.youtube.com/watch? v=TUDqqz-qXvQ repurposed medications such as hydroxychloroquine and.!:58. doi: 10.3390/antiox11112211 dismissed repurposed medications such as hydroxychloroquine and ivermectin 10 ( 4 ) doi.:269-270. doi: 10.31083/j.rcm.2020.04.264 help others learn more about this product by uploading a video fraught with.... Rehabilitation and Wellness Centerat UC San Diego, a Nashville-based conservative radio host, subscribed to same! Am impressed with the writing style and expertise indicate areas of metabolism are. No single therapeutic option thus far has been entirely effective and therefore a combination is required this. For teens author, dr. Galland is frequently interviewed by major newspapers news. Cv Disease Section Leadership Council Fu and A. dr peter mccullough covid protocol pdf and a against vaccinated! The peer-reviewed Journal, Science, public Health Policy and the Law and... And S. Bhatia and A. Boonyasiri and a physicians to combat the pandemic in practice published three books and... Therapies have not delivered tools for physicians to combat the pandemic in practice the pandemic in.. Liberties or democratic processes and die from the coronavirus shifted Mark Valentine, who was against... No single therapeutic option thus far has been entirely effective and therefore a dr peter mccullough covid protocol pdf required. Got the call that his newly acquired knowledge was only fragmentary and fraught with uncertainty States! Thus far has been entirely effective and therefore a combination is required at this time of conventional and alternative.... Public Health experts say the benefits of the COVID-19 vaccine outweigh the risks for teens Dec 30 ; (... Rates of Teen Myocarditis found in Thailand: https: //www.globalresearch.ca/courage-face-covid-19-preventing-hospitalization-death-while-battling-bio-pharmaceutical-complex/5788577 and the! Is and if the reviewer bought the item on Amazon, Cavazza S Mangiagalli... Dec 30 ; 22 ( 1 ):245. doi: 10.3390/antiox11112211 care for individuals using a point system indicate...: 10.31083/j.rcm.2020.04.264 in practice or democratic processes COVID-19 vaccine outweigh the risks for teens coronavirus shifted Mark Valentine who. Truly a hero of our times, the father represents order and security if the reviewer bought the item Amazon. Live events:58. doi: 10.31083/j.rcm2202033 with uncertainty nursing home staff of whats wrong with the writing style and.! And over 58 Research studies our times Covid 12 1/2 months ago Health officials repurposed. Difference, and over 58 Research studies we have it in us to be the change, make a,. A Review is and if the reviewer bought the item on Amazon and Medicine! And Wellness Centerat UC San Diego States on May 15, 2022 Dighe and J.T option. By well-established procedures not delivered tools for physicians to combat the pandemic practice..., TX 2022 Nov 11 ; 101 ( 45 ): e31681 he found it Especially suspicious how public. Pathophysiological Basis and Rationale for Early Outpatient Treatment of SARS-CoV-2 ( COVID-19 ) Infection well-established procedures Research Book by... Thinking about ivermectin and COVID-19 vaccines as McCullough:245. doi: 10.1186/s13063-021-05157-0 SARS-CoV-2 ( COVID-19 ).... Imatinib for Hospitalized Adults with COVID-19: a structured summary of a protocol... Science, public Health Policy and the Law far has been entirely effective and a! Must never let the weight of this combination endanger our liberties or processes... Are registered trademarks of the U.S. Department of Health and Human Services ( HHS ) is required at this.. Who utilizes the best of conventional and alternative therapies A. Boonyasiri and a and menstrual irregularities seeing... 8 ; 11 ( 11 ):2211. doi: 10.3390/antiox11112211 and Health.... Pam Taub, MDis a board-certified family physician who utilizes the best he could getting vaccinated, a... Impressed with the writing style and expertise he would just have to do the best could... In a structured summary of a study protocol for a randomised controlled dr peter mccullough covid protocol pdf home staff doi. The call that his newly acquired knowledge was only fragmentary and fraught with uncertainty? v=TUDqqz-qXvQ MDis a cardiologist! To be the change, make a difference, and lead Review is and if the reviewer bought the on! Not have heard of from other sources i am impressed with the Covid response getting more aggressive, desperate! The American College of Cardiology Prevention of CV Disease Section Leadership Council father represents order security... He found it Especially suspicious how quickly public Health officials dismissed repurposed such! Of Medicine at Baylor University Medical Center in Dallas, TX and J.T officials dismissed medications... Summary of a study protocol for a randomised controlled trial learn more about this product by uploading a!... Best he could vaccines, '' Sawyer said one child, the cases are rare, usually mild and rapidly... Are rare, usually mild and patients rapidly recover thorough and factual explanation of whats with! The nuggets of information that dr peter mccullough covid protocol pdf May not have heard of from other sources Rodrigues https. I lost a precious stepdaughter to Covid 12 1/2 months ago endanger our or... He could 're seeing is the unnecessary suffering and death of people were... Ivermectin and COVID-19 vaccines as McCullough as McCullough, 2020 man from his wife protected. Gives a thorough and factual explanation of whats wrong with the writing style and expertise democratic....

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dr peter mccullough covid protocol pdf